Exactly like a neck position single coil? No.

Your best bet for a single pick up guitar? Yes.

If you have a tone control - Just hook the Q-filter up to that per instructions and turn the tone down to get the sound that you want. It will essentially go from L-500XL sound to approximated PAF to approximated strat single-coil and all points in between. The only sound that you will not be able to approximate is the soapbar sound.