Hey Dave,
Yeah, I have the guitar wired in the Jimmie Vaughan wiring setup, I think the Eric Johnson strat is wired similarly, tone on neck and bridge, no tone on middle.
I've had a 500K in there to squeeze a little more life out of the 280sn I've got now, but from reading up on these pickups, I gathered I'd have to go with a 250K in there. I prefer the taper of a 250K anyhow.